Manaus on the map.

Manaus (/mɑːˈnaʊs/; Portuguese: [mɐˈnaws, mɐˈnawʃ]) is the capital and largest city of the Brazilian state of Amazonas. It is the seventh-largest city in Brazil, with an estimated 2019 population of 2,182,763 distributed over a land area of about 4,401.97 square miles (11,401 km2). Located at the east center of the state, the city is the center of the Manaus metropolitan area and the largest metropolitan area in the North Region of Brazil by urban landmass. It is situated near the confluence of the Negro and Solimões rivers.

The city was founded in 1669 as the Fort of São José do Rio Negro. It was elevated to a town in 1832 with the name of "Manaus", an altered spelling of the indigenous Manaós peoples, and legally transformed into a city on October 24, 1848, with the name of Cidade da Barra do Rio Negro, Portuguese for "The City of the Margins of the Black River". On September 4, 1856 it returned to its original name.

Manaus is located in the center of the world's largest rainforest, and home to the National Institute of Amazonian Research, being the most important center for scientific studies in the Amazon region and for international sustainability issues.